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Crumble all the cupcakes into a large bowl, then start with ¼ cup of the frosting and mash everything together by hand. Form 20 2-inch balls by rolling the mixture tightly between the hands. If the mixture is too crumbly, add more frosting a few tablespoons at a time. Too much frosting will create super sticky cake pops that are difficult to dip.
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Melt about ½ cup of white candy wafers according to their instructions. Dip a cake pop stick about one inch into the melted coating, then push it halfway through a cake pop. Repeat with each cake pop, then cover tightly with plastic wrap and chill for at least 4 hours.
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Melt enough candy wafers in a dish to a depth of at least an inch deeper than the cake pop’s size. In one motion, dip a cake pop until it’s completely covered and pull it back out, being careful not to stir the melted candy with the cake pop. Gently tap off any excess, and spin the cake pop if necessary to stop drips. After about 30 seconds, place a candy wafer on the cake pop to create the iris of the eyeball. Place in a cake pop stand or foam brick to harden, and repeat with remaining cake pops, keeping undipped cake pops covered at all times.
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Once cake pops are hard, mix the gel colors per the instructions. To get vibrant colors use less water - start with just a drop and mix with the powder thoroughly before adding more.
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Draw blood vessels using red gel with a paint brush, color the iris with green, draw the iris using black, and use the remaining melted white candy wafers to create a reflection spot over each pupil.